Most who supplement with Arimidex will be doing so for the prevention of side-effects while on cycle or to tighten up their physique for a physique based competition by reducing estrogen in the body. Most men will find every other day to be a good starting point while on cycle if it is needed for side-effect prevention with 1mg every other day generally being the most anyone will ever need for this purpose. However, if side-effects begin to manifest, particular Gynecomastia, many find supplementing with 1mg every day for a few weeks to be useful in combating this enemy; however, for this purpose we would in most cases recommend the slightly stronger AI Letrozole but Arimidex will often suffice. If this occurs, simply supplement with 1mg every day until symptoms pass; once they do drop the dose to every other day and finish your intended cycle. It should be noted, this is not a 100% failsafe plan; for some no amount of any AI on earth will protect from Gynecomastia.