Anastrozole has no harsh side effects. Actually, affecting estradiol, it can suppress the level of the good cholesterol (HDL). However, when compared to AI like letrozole, anastrozole is preferable. Letrozole has quite a few side effects, the most common of which is erectile dysfunction. Although estradiol is known as a female hormone, men still need it. Estradiol maintains hormonal balance, participates in a great number of physiological processes and helps to gain muscle mass and strength. Such potent AI as letrozole kills almost all estradiol, disrupting the hormonal balance and causing a number of side effects, such as erectile dysfunction, joint pain, bones fragility, unwellness, etc. Anastrozole acts more smoothly and does not kill all estradiol immediately, allowing you to more finely adjust the hormonal balance.
Dave, let me clear the air here on some of the confusion… I recommend the 1 vial cycle for someone who is either A. younger or either B. already has high levels of natural testosterone. Now, the typical middle aged male who already had declining levels of natural testosterone COULD go with 500 mg/wk for 10 wks. Recovery is recovery at that point and if you’re going to do it then I see nothing wrong with getting the most out of that first cycle. But what you have to realize is a male with a starting level of high average test levels can still yield the same benefits of someone who is middle range-low end of normal and uses 500mg/wk of test. In either case the person can still gain a solid 20 lbs of muscle from either 1 or 2 vials, the determining factor on this is what they were at to begin with