One theory is that the estrogen increase/decrease from boron supplementation depends on the amount of aromatization (conversion of testosterone to estrogen) going on in the body. The evidence on boron is conflicting but it concludes one thing – there’s an increase in testosterone. Now a man with a belly or a higher body fat %, or a man eating a lot of estrogenic foods or being exposed to a lot of estrogenic chemicals will have more aromatization going on and therefore convert more of that testosterone generated from boron into estrogen. Maybe take boron only when you’re lean. That’s just a theory though, try it out and see how you feel.
What is less known is that dietary fat helps to promote anabolism. Specifically, the fats you consume impact testosterone levels . The importance of testosterone in building muscle is incontrovertible. There is clear evidence that testosterone increases protein synthesis and attenuates protein breakdown, 32, 37 as well as potentiating the release of other anabolic factors such as growth hormone 33 and IGF-1 . 30 Interestingly, studies show that testosterone levels are suppressed with the consumption of low-fat diets. 11 Polyunsaturated fatty acids, in particular, have been found to enhance testosterone function. 15 Here’s the kicker: lifting weights appears to heighten these testosterone-boosting effects 27 ; in other words, fat intake and resistance training have synergistic effects on anabolism. All things considered, at least 20 percent of your calories should come from dietary fat.
Testosterone can be administered parenterally , but it has more irregular prolonged absorption time and greater activity in muscle in enanthate , undecanoate , or cypionate ester form. These derivatives are hydrolyzed to release free testosterone at the site of injection; absorption rate (and thus injection schedule) varies among different esters, but medical injections are normally done anywhere between semi-weekly to once every 12 weeks. A more frequent schedule may be desirable in order to maintain a more constant level of hormone in the system.  Injectable steroids are typically administered into the muscle, not into the vein, to avoid sudden changes in the amount of the drug in the bloodstream. In addition, because estered testosterone is dissolved in oil, intravenous injection has the potential to cause a dangerous embolism (clot) in the bloodstream.